OncoSeek®
Multi-cancer early detection blood test
When cancer is diagnosed early, mortality and patient burden during treatment can be reduced. At SeekIn, we are committed to making accurate, affordable, and accessible cancer early detection services to individuals
worldwide.
OncoSeek® was established using artificial intelligence (AI) to distinguish cancer from non-cancer cases by calculating the probability of cancer (POC) index based on the quantification results of seven protein tumor markers (PTMs) and clinical information including gender and age of the subjects. And prediction the possible affected tissue of origin (TOO) who has been detected with cancer signal.
Highlights
- OncoSeek® is a machine learning algorithm that uses the results of a simple blood test to detect 9 highmortality cancer types by analyzing the concentration of a panel of protein tumour markers.
- The algorithmanalyzes the specific relations between markers and clinical factors, significantly reducing false positives whencompared to the standard analysis of multiple individually evaluated protein tumour markers.
- The averagesensitivity is 51.7% with a specificity of 92.9%. The test also gives an indication for the tissue of origin whichguides the subsequent diagnostic steps.
A large cohort study (nearly 10,000 participants) confirmed that OncoSeek significantly outperformed the conventional clinical method, representing a novel blood-based test for multi-cancer early detection (MCED) which is a non-invasive, easier, efficient, and robust approach. The data showed that the conventional clinical method relied only on a single threshold for each PTM which would make a big problem that was when combining the result of those markers, the false positive rate would accumulate as the number of tests increased. Nevertheless, AI algorithms play a key role in OncoSeek approach, which makes it possible to do multiple cancer screenings based on PTMs. Moreover, this method can accurately trace the origin of cancer which facilitates the follow-up diagnostic workup.
How it works
Customer order
Customers can place orders through SeekIn official website or local agents
Blood-draw
4 ml venous peripheral blood collected in cell-free DNA BCT and can be stably stored at room temperature for 7 days
Testing
Detection by Roche cobas e411 instrument
Reporting
The test results will be ready in about 5 workdays after your blood draw arrived at central lab
