OncoSeek®
Multi-cancer early detection blood test
When cancer is diagnosed early, mortality and patient burden during treatment can be reduced. At SeekIn, we are committed to making accurate, affordable, and accessible cancer early detection services to individuals worldwide.
OncoSeek® was established using artificial intelligence (AI) to distinguish cancer from non-cancer cases by calculating the probability of cancer (POC) index based on the quantification results of seven protein tumor markers (PTMs) and clinical information including gender and age of the subjects. And prediction the possible affected tissue of origin (TOO) who has been detected with cancer signal.
Highlights
- OncoSeek® is a machine learning algorithm that uses the results of a simple blood test to detect 14 high mortality cancer types by analyzing the concentration of a panel of protein tumour markers.
- The algorithm analyzes the specific relations between markers and clinical factors, significantly reducing false positives when compared to the standard analysis of multiple individually evaluated protein tumour markers.
- The average sensitivity is 58.4% with a specificity of 92.0%. The test also gives an indication for the tissue of origin which guides the subsequent diagnostic steps.
An international, multi-center clinical trial has validated the effectiveness of OncoSeek®. The study involved seven prominent medical centers across Brazil, China, and the United States, enrolling 15,122 participants (including 3,029 cancer patients and 12,093 non-cancer controls). Testing was conducted on four laboratory platforms with both serum and plasma samples.
OncoSeek® proved highly effective, detecting 14 major cancer types—including those responsible for over 72% of worldwide cancer mortality, such as lung, liver, colorectal, pancreatic, stomach, and breast cancers. Sensitivity varied from 38.9% to 83.3% depending on cancer type.
How it works
Order
Consult your doctor to order through a local healthcare partner
Blood draw
4 mL of peripheral blood is collected and delivered to the central lab
Testing
Detection is performed using immunoassay platforms, such as Roche Cobas
Reporting
Results are ready within 5 working days after the sample arrives at the central lab
