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seek and you will find

  • Home
  • Technology
  • Products 
    • Products Overview
    • SeekInCare
    • SeekInCure
    • SeekInClarity
    • OncoSeek
    • LeukoPrint
    • PanCanSeek
    • LungCanSeek
    • PetCanSeek
  • Publication 
    • Research
    • Others
  • Newsroom
  • Product & Service Inquiry
  • …  
    • Home
    • Technology
    • Products 
      • Products Overview
      • SeekInCare
      • SeekInCure
      • SeekInClarity
      • OncoSeek
      • LeukoPrint
      • PanCanSeek
      • LungCanSeek
      • PetCanSeek
    • Publication 
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  • LeukoPrint®

    Hematologic Malignancy Molecular Karyotyping Test

    LeukoPrint® is a molecular karyotyping test designed to complement conventional cytogenetic approaches in hematologic malignancy diagnostics. lt employs shallow whole-genome sequencing (sWGS) to deliver comprehensive, high-resolution genome coverage for the detection of clinically significant copy number aberration (CNA) and copy neutral loss of heterozygosity (CN-LOH), providing advantages over traditional karyotyping and fluorescence in situ hybridization (FlSH).

    Molecular karyotyping

    Precision diagnosis

    Risk stratification

    Therapy guidance

    How it works

    • LeukoPrint® performs shallow whole-genome sequencing (sWGS, at 1× coverage) on bone marrow samples to identify genome-wide CNA and CN-LOH.
    • When combined with traditional cytogenetic methods, it enables more accurate diagnosis,classification, risk-stratification, and ultimately guides risk-adapted therapy for hematologic malignancies.
  • Key advantages of LeukoPrint®

    ◉ No cell culture

    Faster results, no culture failures.

    ◉ Genome-wide CNA/CN-LOH

    Sensitive, automated detection of key abnormalities missed

    by standard methods.

    ◉ Greater diagnostic yield

    Accurately detects small CNAs (≥1 Mb) even in low-tumor or

    ambiguous samples.

    ◉ Clinical actionability

    Supports risk-adapted therapy with ELN/IPSS-/mSMART

    integration.

  • When to use LeukoPrint® test

    First-line diagnostic adjunct

    enhances sensitivity in

    suspected hematologic

    malignancies.

    Karyotyping failure rescue

    provides full genomic profiling when standard

    karyotyping fails.

    Complex case resolution

    reveals cryptic abnormalities when karyotyping/FISH

    are inconclusive.

    Critical variant detection

    identifies CN-LOH

    undetectable by

    karyotyping/FISH.

  • What do you need to know

    ◉ Indicated subjects:Patients with suspected or confirmed hematologic malignancies

    ◉ Sample requirement:2-4ml bone marrow

    ◉ Result readout:CNA and CN-LOH

    ◉ Turnaround time (TAT):10 working days

  •  

    How does the process work

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    Customer order

    Customers can place orders through SeekIn official website or local agents

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    Blood-draw

    2-4ml bone marrow collected in EDTA tubes and ransport under refrigeration

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    Testing

    Detection by next generation sequencing (NGS) platform

    Section image

    Reporting

    The test results will be ready in about 10 workdays after your blood draw arrived at central lab

  • Please review the instructions to gain a better understanding of LeukoPrint® and assess whether it meets your needs.

    Download the Instructions

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